Is anti p1 clinically significant?
Furthermore, what is anti p1 antibody? Anti-P1 is typically a clinically insignificant IgM antibody that does not react at temperatures >25 °C [3]. However, rare cases of severe acute and severe delayed hemolytic transfusion reactions (HTRs) caused by anti-P1 antibodies reactive at 37 °C have been reported [4,5,6,7,8].